Treatment of Sleep Disturbance in Children With ASD
Status:
Not yet recruiting
Trial end date:
2023-06-30
Target enrollment:
Participant gender:
Summary
This RCT study aims to compare effectiveness physical exercise and melatonin supplement on
treating sleep disturbance in children with ASD. A four-arm randomized controlled trial with
equal allocation ratio to the three intervention groups (i.e., jogging; melatonin supplement,
combine jogging and melatonin supplement) and one placebo-control group will be conducted .
Actigraph device and sleep log will be used for sleep assessment. 6-sulfoxymelatonin from
24-h and first morning urinary samples. The investigators will monitor the changes of four
sleep parameters (sleep onset latency, sleep efficiency, wake after sleep onset and total
sleep duration) and the 24-h and first morning melatonin level throughout the whole study.
Phase:
N/A
Details
Lead Sponsor:
Education University of Hong Kong
Collaborators:
Castle Peak Hospital Chinese University of Hong Kong United Christian Hospital University of Leicester