Treatment of Ulcerative Colitis With Ciprofloxacin and E. Coli Nissle

• Status: Completed
• Trial end date: 2013-08-01
• Target enrollment: 0
• Participant gender: All

Summary

Purpose: The purpose of the study is to investigate if treatment with ciprofloxacin for one week followed by therapy with E. Coli Nissle (EcN) for seven weeks can influence disease activity among ulcerative colitis patients with disease flare-ups compared to placebo controls.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hvidovre University Hospital
• Treatments: Ciprofloxacin

Criteria

Inclusion Criteria:

• Age, >/=18 years and diagnosed with ulcerative colitis

• CAI score of >/=6 (active UC)

Exclusion Criteria:

• Pregnant or breastfeeding females

• Known sensitivity to ciprofloxacin

• Subjects who participate in another clinical trial

• Positive stool sample with any enteric pathogens, parasites or Clostridium difficile

• Treatment with systemic corticosteroids or biologic therapy