Treatment of Vitamin D Deficiency With Large Bolus Cholecalciferol

• Status: Terminated
• Trial end date: 2021-01-15
• Target enrollment: 0
• Participant gender: All

Summary

Comparing two treatment regimens (solitary large dose vs daily smaller dose) in patients diagnosed with vitamin D deficiency.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Parkview Adult Medical Center; Parkview Medical Center
• Treatments: Cholecalciferol; Vitamin D

Criteria

Inclusion Criteria:

• age 18-75yrs old

• serum 25(OH)-vitamin D level <20ng/mL

• patient of Parkview Adult Medicine clinic

• not currently on cholecalciferol >2,000IU daily

• no ergocalciferol administration within last week

Exclusion Criteria:

• history of hypercalcemia or hyperparathyroidism

• history of chronic kidney disease with baseline creatinine >1.1

• history of gastric absorption abnormalities

• history of Paget's disease or osteomalacia

• history of thyrotoxicosis

• known malignancy

• currently pregnant

• taking medications for osteoporosis or seizures

• taking more than 1200mg/day of calcium

• inpatient hospitalization at the initiation of study meds