Tri-split Face Study of Skin Resurfacing Modalities for the Treatment of Melasma

• Status: Withdrawn
• Trial end date: 2022-09-01
• Target enrollment: 0
• Participant gender: All

Summary

Tri-split face study of skin resurfacing modalities for the treatment of melasma, comparing the medium depth trichloroacetic acid peel, CO2 laser and Qs-NdYag laser.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: SUZAN OBAGI; University of Pittsburgh

Criteria

Inclusion Criteria:

• male or female participants

• 20 to 60 years old

• participants with melasma on forehead and both cheeks

• participants who failed topical therapy for melasma

• participants who have never tried other therapies for melasma

Exclusion Criteria:

• pregnancy

• lactation

• use of oral contraceptive (OCP) within 3 months of starting the study

• hormonal therapy within 3 months of starting the study

• hormonal intrauterine device (IUD) within 3 months of starting the study

• history of poor wound healing or abnormal scarring

• history of lip or face herpes simplex virus infections

• active facial skin infection

• history of connective tissue disorders (such as lupus or scleroderma)

• history of isotretinoin therapy within 6 months of starting the study

• history of chemical peels, dermabrasion, laser therapy or intense pulse light (IPL) within 6 months before enrollment into the study