Trial Between a Computer-Guided Insulin Infusion Protocol Versus a Standard Insulin Infusion Algorithm in Medical ICU
Status:
Completed
Trial end date:
0000-00-00
Target enrollment:
Participant gender:
Summary
High blood sugars increase the risk of complications and death in diabetic patients admitted
to the hospital. Recent studies hve shown that strict blood sugar control with intravenous
(IV) insulin lowers the risk of such complications and death in the ICU. Several insulin
infusion protocols have been reported in the literature, but it is not known which is the
best. These protocols use tables and formulas that may be confusing and difficult to follow.
To facilitate patient care, insulin protocols could be placed on a computer and used at the
patient's bedside to direct the nursing staff administering the IV insulin. The Glucommander
is one of such computer-derived insulin infusion protocol which has been used successfully
in patients with diabetes since 1984. We hypothesize that management of inpatient
hyperglycemia with a computer-guided intravenous infusion protocol will facilitate smoother
glycemic control with a lower rate of low blood sugars than treatment following a standard
insulin infusion algorithm in the medical intensive care unit. We will aim to determine
differences in glycemic control between treatment with a computer-guided intravenous
infusion protocol (Glucommander) and a standard insulin infusion algorithm in critically ill
patients in the ICU.
Phase:
N/A
Details
Lead Sponsor:
Emory University
Collaborators:
Grady Memorial Hospital, Atlanta Piedmont Hospital, Atlanta Sanofi University of Tennessee