Trial Comparing Ferric(III)Carboxymaltose Infusion With Oral Iron Suppletion as Treatment of Anaemia
Status:
Unknown status
Trial end date:
2019-12-01
Target enrollment:
Participant gender:
Summary
The aim of this multicenter trial is to determine the efficacy of preoperative intravenous
iron suppletion in comparison with the standard preoperative oral substitution in anaemic
patients with colorectal cancer in curing the anemia and the assess the effect of
preoperative iron on morbidity, postoperative recovery and quality of life.
Hypothesis: It is our hypothesis that a more profound approach of preoperative anaemia with
intravenous iron will lead to a higher percentage of patients with normalization of Hb-level
(> 12 g/dl (7.5 mmol/l) for women and > 13 g/dl (8 mmol/l) for men), which potentially
reduces morbidity, length of stay, improves quality of live, decreases fatigue and could be
more cost effective compared to current practice with oral substitution of iron.
Phase:
Phase 4
Details
Lead Sponsor:
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)