Trial Comparing Intravenous and Oral Moderate Sedation for First Trimester Surgical Abortions
Status:
Terminated
Trial end date:
2008-11-01
Target enrollment:
Participant gender:
Summary
In the United States, the majority of first-trimester surgical abortions are performed in
outpatient clinics that utilize a wide variety of oral and intravenous regimens for pain
control. The specific aim of this study is to evaluate the equivalency of intravenous
moderate sedation (fentanyl 100 mcg and midazolam 2 mg) versus oral analgesia/anxiolysis
(lorazepam 2 mg sublingual, hydrocodone/acetaminophen 5/500 mg, and ibuprofen 800 mg) for
first-trimester surgical abortions. The investigators hypothesize that oral moderate sedation
and intravenous moderate sedation will be equivalent in controlling pain as measured by a
difference of +/- 10 on a 100-point (range 0-100) visual analog pain scale.