Trial Evaluating multimOdal toPical Cream In CompArison to pLacebo (TOPICAL)

• Status: Terminated
• Trial end date: 2018-05-30
• Target enrollment: 0
• Participant gender: All

Summary

Randomized controlled trial regarding the efficacy of a multimodal topical analgesic, Multiprofen, in comparison to placebo cream treatment on knee pain and function in patients with knee osteoarthritis.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Michigan
• Collaborators: McMaster University; Oakville Trafalgar Memorial Hospital

Criteria

Inclusion Criteria:

The inclusion criteria are:

1. adult men or women ages 50-80 years;

2. Diagnosis of symptomatic osteoarthritis of the knee based on clinical and radiographic criteria;

3. provision of informed consent.

Exclusion Criteria:

The exclusion criteria are:

1. patients with inflammatory osteoarthritis;

2. open wounds or sores over the knee joint;

3. patients that will likely have problems, in the judgment of the investigators, with maintaining follow-up;

4. Cases involving litigation.