Trial Of Irinotecan In Combination With Three Methods Of Administration Of Fluoropyrimidine.
Status:
Completed
Trial end date:
2008-10-01
Target enrollment:
Participant gender:
Summary
This study compares in the first study period combination of Irinotecan with three different
methods of administration by Fluoropyrimidine. (ie. infusion, bolus and oral). In the second
period of study it compares FOLFIRI [a chemotherapy regime that combines bolus irinotecan and
leucovorin [LV] with infusional 5-fluorouracil (5-FU)] + bevacizumab and mlFL + bevacizumab.
Measures of efficacy and safety will be reported.