Trial and Follow-up of the Efficacy of Two-stage Integrated Treatment for Chinese Schizophrenia Inpatients

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

Regular psychosocial intervention combined with antipsychotic drugs, compared with usual medication alone treatments, can reduce psychiatric symptoms and improve quality of life in patients with schizophrenia. However, it's expensive, time-consuming, and sometimes inconvenient for patients and their family members in developing areas where the number of well-trained therapist remains limited in local psychiatric settings. The investigators aimed to establish an efficient model of integrated treatment (IT) for patients with schizophrenia. The procedure contains two stages: a centralized treatment during hospitalization and the following consolidation treatments with long intervals.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Guangzhou Psychiatric Hospital
• Treatments: Antipsychotic Agents; Olanzapine

Criteria

Inclusion Criteria:

• Diagnosed with the Structured Clinical Interview for DSM-IV (SCID-DSM-IV) (First et al., 1996), were recruited from inpatient psychiatric ward. Patients with diagnoses of schizoaffective or other psychotic disorders were not included.

• Additional inclusion criteria for participants were aged between 18 and 50 years with education of more than 9 years, and

• PANSS (Positive and Negative Syndrome Scale) total scores of more than 60.

Exclusion Criteria:

• Diagnosed with a serious and unstable medical condition including abuse and/or dependence of alcohol and/or drugs;

• Pregnant or breastfeeding;

• Under a treatment of clozapine with a dose of more than 200 mg/day,

• Had a treatment of the electroconvulsive therapy (ECT) or modified electroconvulsive therapy within 6 months(MECT) within the past six months.