Overview

Trial for Treatment of Adult Patients With Standard Risk Acute Lymphoblastic Leukemia With Chemotherapy and Rituximab

Status:
Completed
Trial end date:
2009-03-01
Target enrollment:
Participant gender:
Summary
The study evaluates the efficacy and tolerability of an intensified induction and consolidation therapy in combination with rituximab in CD20 positive standard risk patients. Thereafter patients receive additional consolidation and reinduction cycles combined with rituximab. In parallel minimal residual disease is evaluated. After six months and one year the decision on intensification or discontinuation of therapy is made based on results of MRD evaluation
Phase:
Phase 4
Details
Lead Sponsor:
Johann Wolfgang Goethe University Hospital
Treatments:
6-Mercaptopurine
Asparaginase
Cyclophosphamide
Cytarabine
Daunorubicin
Dexamethasone
Doxorubicin
Mercaptopurine
Methotrexate
Prednisolone
Rituximab
Thioguanine
Vincristine
Vindesine