Trial of Acquired Haemophilia With Steroid Combined With Cyclophosphamide Versus Steroid Combined With Rituximab
Status:
Recruiting
Trial end date:
2021-12-01
Target enrollment:
Participant gender:
Summary
Purpose:
To evaluate the efficacy when administering steroid combined with single dose rituximab to
eliminate the antibody in acquired hemophilia A patients compared to treatment using steroid
with cyclophosphamide.
The study will test the hypothesis that steroid combined with small dose rituximab is as
effective as steroid combined with cyclophosphamide for FVIII inhibitor eradication in
Chinese patients with acquired hemophilia A.
Study design Allocation: Randomized Intervention Model: Parallel Assignment Masking: None
(Open Label) Primary Purpose: Treatment
Phase:
Phase 3
Details
Lead Sponsor:
Zhang Lei
Collaborators:
Henan Cancer Hospital Qilu Hospital of Shandong University The Second Affiliated Hospital of Kunming Medical University Tianjin First Central Hospital