Trial of Cyclosporine for Myocardial Protection During Open Heart Surgery
Status:
Terminated
Trial end date:
2010-10-01
Target enrollment:
Participant gender:
Summary
Administration of cyclosporine has been found to have a myocardial protective effect,
improving post-operative cardiac function in patients undergoing percutaneous coronary
interventions by diminishing infarct size. The purpose of the proposed study is to conduct a
randomized, controlled clinical trial in patients undergoing isolated valvular heart surgery,
or coronary artery bypass surgery. Specifically the investigators will evaluate the
cardio-protective effects of cyclosporine on post ischemic-arrest myocardium. The two factors
will be treatment group and cyclosporine versus placebo.
Phase:
Phase 1
Details
Lead Sponsor:
The University of Texas Health Science Center, Houston