Trial of Naproxen Sodium for the Treatment of OCD in Children With PANDAS
Status:
Recruiting
Trial end date:
2022-10-31
Target enrollment:
Participant gender:
Summary
This project aims to rigorously evaluate a potential treatment for inflammation-related
Obsessive-Compulsive Disorder (OCD) symptoms in children. To accomplish this goal, the
investigators will conduct a double-blind, randomized, placebo-controlled trial of Naproxen
Sodium, a nonsteroidal anti-inflammatory drug (NSAID) in participants diagnosed with
Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal infections
(PANDAS). This research fills a gap in the empirical evidence base for the treatment of
PANDAS, and will add to a growing literature of empirically-derived practices for PANDAS.