Trial to Shorten Pharmacologic Treatment of Newborns With Neonatal Opioid Withdrawal Syndrome (NOWS)
Status:
Recruiting
Trial end date:
2025-08-01
Target enrollment:
Participant gender:
Summary
The objective of this study is to evaluate the efficacy of a rapid wean intervention compared
with a slow-wean intervention in reducing the number of days of opioid treatment from the
first dose of weaning to cessation of opioid among infants receiving an opioid (defined as
morphine or methadone) as the primary treatment for neonatal opioid withdrawal syndrome
(NOWS).
Phase:
Phase 3
Details
Lead Sponsor:
Advancing Clinical Trials in Neonatal Opioid Withdrawal (ACT NOW) Program
Collaborator:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)