Triclosan Toothpaste in the Maintenance Phase of Peri-implantitis Treatment.

• Status: Completed
• Trial end date: 2017-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study was to evaluate the effects of a dentifrice containing 0.3% triclosan on periodontal and peri-implant parameters in patients, with or without periodontitis, treated for peri-implantitis and that were enrolled in a maintenance phase for two years.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Guarulhos
• Collaborator: Universidade Estadual de Maringá
• Treatments: Anti-Infective Agents; Fluorides; Sodium Fluoride; Triclosan

Criteria

Inclusion Criteria:

• aged between 18-70 years;

• general good health;

• minimum of 1 dental implant in function for at least one year with untreated peri-implantitis defined as: probing depth (PD) ≥ 5 mm, bleeding on probing (BOP) or suppuration, radiographic bone loss involving 2 mm from the upper border of the intrabony portion of the implant.

Exclusion Criteria:

• untreated periodontitis (defined as ≥ 6 sites with PD ≥ 5 mm);

• periodontal treatment within three months prior to entering the study;

• inability to perform proper supragingival plaque control (e.g. due to improper prosthesis design or lack of skills);

• diabetes;

• pregnancy;

• nursing;

• history of allergies to triclosan, fluoride or any other ingredient of oral care products;

• alcohol or drug abuse;

• any systemic diseases that could affect post-operative healing;

• any systemic diseases that required antibiotic premedication for routine dental therapy;

• long-term use of mouthrinses, anti-inflammatory medications or any other drug that could interfere with the study outcomes within three months prior to entering the study;

• antibiotics use within six months prior to entering the study;

• participation in any other clinical study within three months prior to entering the study.