Trigonal vs Non Trigonal Botox Injection in OAB.

• Status: Completed
• Trial end date: 2018-05-30
• Target enrollment: 0
• Participant gender: All

Summary

The investigators attend to conduct a prospective randomized study to assess safety and efficacy of trigonal-involved vs. trigonal-sparing botox injection technique, quality of life measurement and post-injection anticholinergics use efficacy.

Assessing safety by identification of side effects like constipation, urine retention....etc.

efficacy is measured using Over Active Bladder Symptoms Score(OABSS) and urodynamics measures after 6 months follow up.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mansoura University
• Treatments: abobotulinumtoxinA; Botulinum Toxins; Botulinum Toxins, Type A; Cholinergic Antagonists; onabotulinumtoxinA

Criteria

Inclusion Criteria:

• Patients with idiopathic OAB refractory to treatment with antimuscarinics for 2 months or intolerable side effects of antimuscrinics

Exclusion Criteria:

• Patients who have any of the following were excluded:

• Age less than 18 year old.

• Neurogenic detrusor overactivity.

• Evidence of obstructed flow in absence of prolapse.

• Mixed urinary incontinence

• Associated urethral pathology, e.g. Urethral diverticulum

• Associated bladder pathology e.g. Fistula.

• Active urinary tract infection as evidenced by positive urine culture.