Tuberculosis Prevention for HIV Infected Adults

• Status: Completed
• Trial end date: 2009-06-01
• Target enrollment: 0
• Participant gender: All

Summary

This study compares three different tuberculosis (TB) prevention regimens against the standard regimen of 6 months of isoniazid. It is being conducted in Soweto, South Africa. People who are HIV positive and have a positive tuberculin skin test without signs of active tuberculosis may join.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
• Treatments: Isoniazid; Rifampin; Rifapentine

Criteria

Inclusion Criteria:

• HIV infected

• Tuberculin test (PPD) positive 5 mm or greater

• Chest x-ray negative for pulmonary tuberculosis

Exclusion Criteria:

• Pregnant or breastfeeding