Overview

Two Combination Chemotherapy Regimens in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia

Status:
Completed
Trial end date:
2020-03-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. It is not yet known which combination chemotherapy regimen is more effective in treating acute lymphoblastic leukemia. PURPOSE: This randomized clinical trial is studying the side effects of two combination chemotherapy regimens and to see how well they work in treating children with newly diagnosed acute lymphoblastic leukemia.
Phase:
Phase 3
Details
Lead Sponsor:
Prince of Wales Hospital, Shatin, Hong Kong
Treatments:
6-Mercaptopurine
BB 1101
Dexamethasone
Dexamethasone 21-phosphate
Dexamethasone acetate
Mercaptopurine
Methotrexate
Vincristine