Two Formulations and Concentrations of Epinastine Nasal Spray Versus Azelastine Nasal Solution for Allergic Rhinitis
Status:
Completed
Trial end date:
2006-10-01
Target enrollment:
Participant gender:
Summary
The objectives of this study were to:
- Examine the tolerability of two formulations and two dose concentrations of epinastine.
- Select formulation(s) of epinastine for future studies by evaluating the individual
sensory attribute scores of the Nasal Spray Evaluation Questionnaire (NSEQ) collected
after each study drug administration and the subject preference ranking assessed at the
completion of the study.
- Compare the preference of two formulations and two dose concentrations of epinastine
compared to azelastine following a single dose of each in a randomized, double-blind,
two-cohort, three-period crossover design.