Two-Point Measurement of Glomerular Filtration Rate by Iohexol Plasma Disappearance

• Status: Completed
• Trial end date: 2016-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to measure glomerular filtration rate (GFR) by iohexol plasma disappearance (gold standard) and measure serum Cystatin C levels (surrogate marker) in patients enrolled in our prospective study at baseline, day 100 and 1 year after hematopoietic cell transplant and determine if these levels correlate with serum creatinine and an estimated GFR using the Modification of Diet in Renal Disease (MDRD) equation and Schwartz formula in children.

• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Washington

Criteria

Inclusion Criteria:

• age > 2 years

• follow-up at Seattle cancer care alliance

Exclusion Criteria:

• age <2 years

• history of diabetes mellitus

• inability to return to the SCCA for follow-up at 1 year

• allergy to iodine