Type 2 Diabetes and the Effect of Probiotics

• Status: Unknown status
• Trial end date: 2007-12-01
• Target enrollment: 0
• Participant gender: Male

Summary

Insulin-resistance in type 2 diabetes is associated with chronic inflammation. Anti-inflammatory actions might increase sensitivity to insulin. Since some probiotics have anti-inflammatory properties, ingestion of the probiotic bacteria Lactobacillus Acidophilus NCFM might increase insulin-sensitivity.

The inflammatory response to endotoxin injection and the insulin-sensitivity is examined before and after four weeks ingestion of probiotics.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Rigshospitalet, Denmark
• Collaborator: Royal Veterinary and Agricultural University, Denmark

Criteria

Inclusion Criteria:

• Healthy

• Type 2 diabetes

Exclusion Criteria:

• Heart failure

• Lung disease

• Infections in the last two weeks before endotoxin injections.

• Treatment with antibiotics