Ulcer Prevention Study in Post Gastric Bypass Patients

• Status: Completed
• Trial end date: 2008-03-01
• Target enrollment: 0
• Participant gender: All

Summary

This research is to determine which medication, Zegerid (Omeprazole/Sodium Bicarbonate) or Pepcid AC (Famotidine), works best at reducing the chance that a patient will get an ulcer after gastric bypass surgery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Missouri-Columbia
• Treatments: Famotidine; Omeprazole; Omeprazole, sodium bicarbonate drug combination

Criteria

Inclusion Criteria:

• Subject is age ≥ 18 years

• Patient meets the criteria for laparoscopic gastric bypass surgery

• Females only: Patient is willing to take a urine pregnancy test

Exclusion Criteria:

• Subject allergic to omeprazole or famotidine

• Patient receiving antifungal (i.e. ketoconazole or itraconazole)

• Hepatic insufficiency

• History of Crohns disease

• History of Zollinger-Ellison disease

• Patient received an investigational drug within 30 days of enrollment

• Patient currently enrolled in another research project

• Females Only: Pregnancy or plan on becoming pregnant during the next 14 weeks