Overview

Ultrasound TFP (Transversalis Fascia Plane) for Analgesia After Iliac Crest Bone Graft Harvest

Status:
Completed
Trial end date:
2018-12-01
Target enrollment:
0
Participant gender:
All
Summary
Iliac crest bone graft harvest is associated with acute pain that can lead to chronic postoperative pain. Local anesthetic infiltration and regional anesthesia could be of interest to reduce opioid consumption during and after surgery, reduce hyperalgesia and the associated risk of chronic postoperative pain. In this surgery, local anesthetic infiltration of the iliac crest is associated with a pain reduction compare with placebo. Some studies have shown the benefit of a TAP (transversus abdominal block) for postoperative analgesia after iliac crest bone graft harvest. The TFP block (transversalis fascia plane block) has been recently described. Considering the nerves trajectories, the TFP block is probably anatomically the most appropriate block for analgesia after iliac crest bone graft harvest. The aim of this study is therefore to assess the benefit of an ultrasound TFP block for analgesia after iliac crest bone graft harvest compare with local anesthetic infiltration Design is prospective, randomized, double blind, controlled study
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Rennes University Hospital
Treatments:
Ropivacaine
Criteria
Inclusion Criteria:

- Age > 18 years

- Patients scheduled for iliac crest bone graft harvest during upper or lower limb
surgery

Exclusion Criteria:

- Allergy to ropivacaine, propofol, paracetamol, remifentanil, morphine, cisatracurium,
ketoprofene, nefopam

- Weight < 50 kg

- Pregnancy

- Severe psychiatric disorder

- Paraplegia or tetraplegia

- Spinal anesthesia

- Contra indication to ketoprofene: age ≥ 75 years, renal insufficiency (creatinine
clearance < 50 ml/min), active gastric ulcer, past of asthma with NSAID

- Contra indication to nefopam: severe cardiac insufficiency, glaucoma, prostate
hypertrophy, epilepsy

- Contra indication to paracetamol: severe hepatic insufficiency

- Severe respiratory insufficiency

- Abnormal hemostasis or anticoagulant treatment

- Chronic use of morphine