Overview

Ultrasound-facilitated, Catheter-directed, Thrombolysis in Intermediate-high Risk Pulmonary Embolism

Status:
Recruiting
Trial end date:
2024-12-01
Target enrollment:
Participant gender:
Summary
There are many available treatments for pulmonary embolism (PE), but the best treatment for this condition is not known. The HI-PEITHO study will compare two treatment options that are both available on the market for the treatment of PE. Patients will be randomized 1:1 to receive either blood thinners (anticoagulation) or blood thinners (anticoagulation) in combination with a device called the EkoSonicTM Endovascular device to dissolve blood clots. Patients will be followed for 12 months after randomization and have assessments while in the hospital as well as at 7 days, 30 days, 6 months and 12 months after randomization. The study will try to find out if one of these treatments is better than the other at reducing the risk of death and other serious problems.
Phase:
Phase 4
Details
Lead Sponsor:
Boston Scientific Corporation
Collaborators:
National PERT Consortium, Inc.
University Medical Center Mainz
Treatments:
Calcium heparin
Heparin