Overview

Umbrella Study of Sasanlimab Combined With Targeted Therapies in Participants With Non Small Cell Lung Cancer

Status:
Recruiting
Trial end date:
2025-12-20
Target enrollment:
Participant gender:
Summary
Phase 1b/Phase 2 open-label, multi-center, parallel group umbrella study. Sasanlimab (a PD-1 antagonist monoclonal antibody) will be combined with a different targeted therapy in each sub-study. The Phase1b part of each sub-study will evaluate the safety of the combination and select the dose for the Phase 2 part. The Phase 2 part of each sub-study will evaluate the anti-tumor activity of the combination.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Pfizer
Treatments:
Axitinib