Understanding How Ketamine Brings About Rapid Improvement in OCD

• Status: Active, not recruiting
• Trial end date: 2022-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to understand how ketamine brings about rapid improvement in Obsessive-Compulsive Disorder (OCD) symptoms.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Stanford University
• Collaborator: University of Connecticut
• Treatments: Ketamine; Midazolam

Criteria

Inclusion Criteria for participants with OCD:

• age 18-65

• Primary diagnosis of OCD

• Sufficient severity of OCD symptoms

• ability to tolerate a treatment-free period

• capacity to provide informed consent

Inclusion criteria for healthy controls:

• ages 18-65

• capacity to provide informed consent

Exclusion criteria for participants with OCD:

• Psychiatric or medical conditions that make participation unsafe

• pregnant or nursing females

• concurrent use of any medications that might increase the risk of participation (e.g. drug interactions)

• presence of metallic device or dental braces

Exclusion criteria for healthy controls:

• any current or lifetime psychiatric diagnosis

• pregnant or nursing females

• major medical or neurological problem

• presence of metallic device or dental braces