Understanding the Increased Risk of Cardiovascular Disease in People With HIV

• Status: Completed
• Trial end date: 2006-01-01
• Target enrollment: 0
• Participant gender: All

Summary

HIV is a virus that can lead to acquired immunodeficiency syndrome (AIDS), a disease for which there is not yet a cure. Antiretroviral therapy (ART) has proven an effective treatment for inhibiting the replication of HIV, allowing for improved quality of life and survival. Previous studies indicate that episodic use of ART is associated with increased risk of cardiovascular disease (CVD). This study will determine mechanisms underlying the increased CVD risk among people infected with HIV and, specifically, in those who receive episodic ART.

• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Minnesota; University of Minnesota - Clinical and Translational Science Institute
• Collaborator: National Heart, Lung, and Blood Institute (NHLBI)
• Treatments: Anti-Retroviral Agents

Criteria

Inclusion Criteria:

• Participant in the SMART study

• CD4+ lymphocyte count greater than 350 cells/mm3

Exclusion Criteria:

• Presence of life-threatening diseases