Unilateral Meniere Disease: Can Double Dose Gadolinium and Delayed Imaging Make the Diagnosis?

• Status: Withdrawn
• Trial end date: 2016-11-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this research study is to see if magnetic resonance imaging (MRI) with a double dose of contrast, or dye, and delayed imaging with MRI can help to diagnose Meniere Disease.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Emory University

Criteria

Inclusion Criteria:

• Diagnosis of unilateral Meniere Disease (MD) per the Committee on Hearing and Equilibrium of the American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS)

• Glomerular filtration rate (GFR) > 90 mls/min/1.73 m2

• Creatinine (Cr) level serum < 1.6 mg/dl

Exclusion Criteria:

• Age < 18 years

• Diagnosis of bilateral MD

• History of prior temporal bone surgery

• History of cochlear implant placement

• Pacemaker, cardiac implantable electronic device, shrapnel, aneurysm clips or other metal objects that are prohibited in the MR suite

• GFR < 90 mls/min/1.73m2

• Cr level > 1.6 mg/d

• Lack of IV access

• Contrast allergy to gadolinium agent

• Pregnancy

• Claustrophobia necessitating parenteral anxiolytics

• Patients who are unable to provide informed consent for themselves