Overview

Uproleselan With Pre-Transplant Conditioning in Hematopoietic Stem Cell Transplantation for AML

Status:
Not yet recruiting
Trial end date:
2028-12-01
Target enrollment:
Participant gender:
Summary
This research study is studying a new drug, uproleselan, to see if it is safe and effective in decreasing relapse after stem cell transplant and improving leukemia-free survival in pediatric patients with acute myeloid leukemia (AML). The name of the study drugs involved in this study are: - Uproleselan - Busulfan - Clofarabine - Fludarabine - Tacrolimus - Methotrexate - Mycophenolate Mofetil
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
John Horan, MD
Collaborator:
GlycoMimetics Incorporated
Treatments:
Busulfan
Clofarabine
Fludarabine