Uric Acid Reduction as a Novel Treatment for Pediatric Chronic Kidney Disease
Status:
Terminated
Trial end date:
2020-10-07
Target enrollment:
Participant gender:
Summary
Aim 1. To determine the effect of Allopurinol treatment on renal function (glomerular
filtration rate, GFR) in pediatric chronic kidney disease (CKD) patients with high uric acid
levels (hyperuricemia).
Aim 2. Establish whether Allopurinol treatment reduces Nlrp3 inflammasome and renal injury
biomarkers.