Ursodeoxycholic Acid in the Treatment of Duodenal Adenomas in Familial Adenomatous Polyposis (FAP) Patients
Status:
Unknown status
Trial end date:
2009-10-01
Target enrollment:
Participant gender:
Summary
Malignant transformation of adenomas of the duodenum is now the leading cause of death in
familial adenomatous polyposis (FAP) patients who had a restorative proctocolectomy.
Ursodeoxycholic acid (UDCA) modifies the biliary acid profile and could reduce the severity
of duodenal adenomas and prevent such transformation.