Use of Budesonide Diluted to Maximum Clinical Treatment of Patients With Chronic Rhinosinusitis With Polyoposis.
Status:
Recruiting
Trial end date:
2025-08-10
Target enrollment:
Participant gender:
Summary
This is a double-blind, randomized, double-blind, randomized, double-blind, randomized block
design with two intervention groups of 30 patients each. Patients not recruited at the
otorhinolaryngology outpatient clinic of the Regional University Hospital of the North of
Paraná and the University Hospital Specialties Ambulatory will be included in the study of
chronic rhinosinusitis with polyposis are randomly divided with stratification for the
presence of two groups of patients. 30 patients, with 9 asthmatics in each). Of the nasal
nasal with 2mg budesonide diluted in high daily volume added to the corticosteroid injectable
injectable and the topic for 16 weeks compared to placebo. The Polyp Score (NPS), Sono-Nasal
Outcome Test-22 (SNOT-22), University of Pennsylvania Olfactory Identification Test (UPSIT),
peak nasal inspiratory flow (PNIF), visual scales preoperative tomography, acoustic
rhinometry, computerized rhinomanometry and nasal endoscopy before and after the treatments.
Position Paper on Nasal Rhinosinusitis and Nasal Polyps 2012; A bilateral nasal pole score is
5 and a maximum of 8 for both nostrils (with less than a score of 2 for each nostril).