Use of Ceftaroline in Hospitalized Patients With Community Acquired Pneumonia
Status:
Completed
Trial end date:
2013-03-01
Target enrollment:
Participant gender:
Summary
Community-acquired bacterial pneumonia, which is often called CAP, is a bacterial infection
in the lungs and is treated with antibiotics. Sometimes people need to be in the hospital to
be treated for CAP. Usually, hospitalized persons with CAP are given two antibiotics
together. These antibiotics usually include a cephalosporin and a macrolide. The most
commonly used cephalosporin at Albany Medical Center Hospital is ceftriaxone. The most
commonly used macrolides at Albany Medical Center Hospital are azithromycin and doxycycline.
This research is being done to find out how well a new cephalosporin antibiotic, called
ceftaroline, works in combination with a macrolide for the treatment of CAP. Ceftaroline is
similar to ceftriaxone. Ceftaroline was recently approved by the FDA to treat pneumonia in
hospitalized patients based on two research studies. In one study, ceftaroline was better
than ceftriaxone. In the second study, ceftaroline was just as good as ceftriaxone.
Ceftaroline was very well tolerated in both clinical studies and it was found to be as safe
as ceftriaxone.
Phase:
Phase 3
Details
Lead Sponsor:
Albany Medical College
Collaborators:
Albany College of Pharmacy and Health Sciences Forest Laboratories