Use of Closed-loop Anesthesia in Pediatric Patients

• Status: Terminated
• Trial end date: 2012-12-01
• Target enrollment: 0
• Participant gender: All

Summary

To compare manual administration of propofol and remifentanil and dual closed-loop using bispectral index as the control variable during pediatric anesthesia

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hopital Foch
• Treatments: Anesthetics; Propofol; Remifentanil

Criteria

Inclusion Criteria:

• class ASA I, II or III

• general anesthesia scheduled to last more than one hour

• intraoperative hemorrhage planned to be less than 15% of the blood volume

Exclusion Criteria:

• Combined general and regional anesthesia,

• Patients with a pacemaker or scheduled for a cardiac or brain surgical procedure,

• History of a neurological or a psychiatric disorder, or central brain lesion,

• Patients receiving a psychotropic treatment or a a morphine agonist-antagonist,

• Allergy to latex, propofol, remifentanil, morphine, muscle relaxant, or to a component,

• Hypersensibility to remifentanil or to a derivate of fentanyl,

• Scheduled postoperative ventilation or sedation.