Use of Epidurals Intraoperatively for Patients Undergoing Pancreas Resection

• Status: Active, not recruiting
• Trial end date: 2023-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to see if there is a difference in complications in patients who have an epidural started earlier (during their surgery) and used as part of the anesthetic in addition to using it for post operative pain compared with patients who receive an epidural later in the surgery to be used only for post operative pain.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Memorial Sloan Kettering Cancer Center
• Treatments: Anesthetics; Bupivacaine; Fentanyl; Propofol; Rocuronium

Criteria

Inclusion Criteria:

• Adult patients ≥ 18 years of age who can provide informed consent

• Scheduled for pancreaticoduodenectomy

Exclusion Criteria:

• Pregnancy

• History of documented anaphylaxis or contraindication to any of the study medications

• Significant cognitive impairment or documented psychologic impairment

• Contraindication to epidural per Pain Service guidelines

• Use of a sustained release opioid medication such as long-acting morphine, fentanyl patches, methadone, and buprenorphine within the last 3 months

• Post randomization exclusion will occur if the patient is found to have unresectable disease at laparotomy and therefore will not have the potential for the same postoperative complications.