Overview

Use of Montelukast to Treat Children With Mild to Moderate Acute Asthma

Status:
Completed
Trial end date:
2008-02-01
Target enrollment:
Participant gender:
Summary
The primary objective of this study is to evaluate if children with acute asthma given a single dose of oral prednisolone with a subsequent daily five-day course of oral Montelukast will achieve a therapeutic failure rate at day 8 not significantly higher than those given six daily doses of oral prednisolone. Secondary objectives include comparison of the two groups with respect to the changes in symptoms, beta2 agonists, clinical asthma score and days without asthma by day 8.
Phase:
Phase 2
Details
Lead Sponsor:
The Hospital for Sick Children
Collaborator:
Merck Frosst Canada Ltd.
Treatments:
Methylprednisolone
Methylprednisolone Acetate
Methylprednisolone Hemisuccinate
Montelukast
Prednisolone
Prednisolone acetate
Prednisolone hemisuccinate
Prednisolone phosphate