Use of N-Acetylcysteine During Liver Procurement

• Status: Completed
• Trial end date: 2009-07-01
• Target enrollment: 0
• Participant gender: All

Summary

Randomized prospective study on the impact on the post-LT outcome by the infusion of N-acetylcysteine (NAC) during the liver procurement procedure, as an anti-oxidant agent to reduce the ischemia-reperfusion damage of organs for liver transplantation (LT).

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Azienda Ospedaliera di Padova
• Treatments: Acetylcysteine

Criteria

Inclusion Criteria:

• all consecutive subjects with chronic liver disease undergoing first Liver Transplantation receiving deceased donor livers

Exclusion Criteria:

• recipients with acute liver disease;

• paediatric patients or adult patients receiving a liver from a paediatric donor;

• patients undergoing multiple-organ transplantation;

• patients undergoing re-transplantation of the Liver;

• patients undergoing living donor Liver Transplantation