Use of Novel Prebiotic Fiber for Targeted Dietary Management of Irritable Bowel Syndrome (Nutrabiotix Phase II)
Status:
Terminated
Trial end date:
2016-04-01
Target enrollment:
Participant gender:
Summary
The objective of this Phase II trial is to test the NTX-1 Fiber in patients with
constipation-predominant IBS (IBS-C) and determine if it can reduce symptoms, beneficially
modify gut microbiota composition, and improve gut milieu in these patients. The
investigators hypothesis for the Phase II study is that NTX-1 Fiber is better tolerated (i.e
has less side effects) and is more effective than psyllium (the most commonly used fiber in
the US) for symptom improvement and is effective in correcting the abnormal colonic milieu in
those with dysbiosis and low SCFA levels.