Use of Ozone Gel as an Antimicrobial in Treatment of Periodontitis

• Status: Completed
• Trial end date: 2022-09-09
• Target enrollment: 0
• Participant gender: All

Summary

Periodontitis is an inflammatory disease that destroys tooth-supporting structures through oral bacterial plaque. ozone gel's act as an antimicrobial effect as an adjunct to conventional periodontal therapy (scaling and root planning). exposure of bacteria to ozone leads to the oxidation of the phospholipids and lipoproteins that comprise the bacterial cell membrane. Ozone gel has the potential to play an anti-inflammatory role in the treatment of periodontitis by monitoring both clinical and biological parameters.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Ghufran Falih Hassan

Criteria

Inclusion Criteria:

• The patient should be systemically healthy

• The patient has periodontitis equal to or more than two non-adjacent teeth, with probing pocket depth equal to or more than 4mm.

• Patients capable of following orders and motivation

Exclusion Criteria:

• Patients with removable dentures who undergo orthodontic therapy.

• Patients with teeth suffer from endo-periodontal lesions.

• Patients have three months of using anti-inflammatory medications, antibiotics, immune suppressants, or oral contraceptives.

• Patients having systemic conditions that affect the condition.

• Pregnant or nursing mothers.

• Patients who are smokers