Use of Ranibizumab With Mitomycin C During Trabeculectomy

• Status: Completed
• Trial end date: 2014-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the study is to study the safety of the combination of ranibizumab and MMC vs monotherapy MMC vs intravitreal ranibizumab injection in patients with glaucoma.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Colorado, Denver
• Collaborator: Genentech, Inc.
• Treatments: Mitomycin; Mitomycins; Ranibizumab

Criteria

Inclusion Criteria:

• glaucoma

• undergoing trabeculectomy

• 21 years of age or older

Exclusion Criteria:

• pregnancy or lactation

• any condition the investigator believes would impose a significant hazard to the patient if investigational therapy were initiated

• history of ocular surface disease

• cataract surgery in the past 6 months

• history of active inflammatory, infectious or idiopathic keratitis