Use of Telmisartan and Captopril in Inflammation of Hemodialysis Patients

• Status: Completed
• Trial end date: 2013-08-31
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study was to compare the dual use of telmisartan and captopril vs the individual use of such drugs and placebo on the systemic inflammation of patients on hemodialysis (HD).

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Coordinación de Investigación en Salud, Mexico
• Treatments: Captopril; Telmisartan

Criteria

Inclusion Criteria:

• Age ≥18 years

• ≥2 months on hemodialysis

• Arteriovenous fistula as vascular access

• Endorsement of informed consent

Exclusion Criteria:

• Inflammatory cause of ESRD

• Liver disease, cancer, AIDS

• Any infectious disease 2 months before the study

• Failed kidney graft

• Hypersensitivity to angiotensin converting enzyme inhibitors or angiotensin receptor blockers

• Arterial hypotension

• Pregnancy

• Treatment with antibiotics, non-steroidal anti-inflammatory drugs, steroids, immunosuppressives, statins, ACE inhibitors or ARB 3 months previous to the study