Use of Topical Lidocaine to Reduce Pain in Preterm Infants Receiving Nasal CPAP Continuous Positive Airway Pressure

• Status: Completed
• Trial end date: 2014-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The main purpose of this study is to evaluate the relative efficacy of topical lidocaine on reducing pain associated with the application of nasal CPAP in preterm infants

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mansoura University Children Hospital
• Treatments: Lidocaine

Criteria

Inclusion Criteria:

• Preterm infants < 37 weeks gestation

• Admitted to NICU, Mansoura University Children's Hospital

• Respiratory distress requiring use of nasal CPAP

• Informed consent obtained

Exclusion Criteria:

• Serious, life-threatening malformations

• Use of sedation, analgesia in the preceding 72 hours

• Those who undergo any surgical intervention

• Those who undergo any painful procedures as venipuncture, intubation, suctioning, blood sampling, heel-prick, catheterization 30 minutes before assessment

• Those with signs of nasal injuries at the time of application of nCPAP

• Necrotizing enterocolitis