Use of Topical Olive Oil Cream for Prophylaxis Against Acute Radiodermatitis in Breast Cancer Patients
Status:
Recruiting
Trial end date:
2022-06-01
Target enrollment:
Participant gender:
Summary
This study aims to compare the prophylactic effect of topical betamethasone valerate cream
and topical olive oil cream in the prevention of acute radiation dermatitis (ARD) in breast
cancer patients treated with radiation. Betamethasone valerate, olive oil cream and the base
cream will be compared in a randomized trial to evaluate and compare the development and
degree of ARD grading according to Radiation Toxicity Grading (RTOG) skin toxicity score,
percentage of patients with the maximum observed ARD grade for each arm of the study,
percentage of patients with moist desquamation for each arm of the study, percentage of
radiodermatitis-free patients at end of therapy (EOT=time point specifically at end of 2
weeks post radiation therapy). In addition, the patients' quality of life will be evaluated
using Dermatology Life Quality Index (DLQI).