Use of Vagitories Based on St. John's Wort, Tea Tree Oil and Shepherd's Purse in the Treatment of Vaginal Inflammation
Status:
Completed
Trial end date:
2019-09-30
Target enrollment:
Participant gender:
Summary
There are more and more herbal preparations that are used for the purpose of treatment and
improvement of the clinical picture of vaginitis by patients themselves, but also by
healthcare professionals. Plant species, St. John's wort, chamomile, calendula, yarrow,
shepherd's purse and tea tree oil are well known for there anti-inflammatory, antimicrobial
and wound healing activity. This paper presents the results of a clinical study in which
three herbal formulations/vagitories, based on extracts of above mentioned plant species,
were investigated for their effectiveness on non-specific vaginitis.
This was randomized controlled clinical study that included 210 women with diagnosed
non-specific vaginitis. Patients were divided into two basic groups, women in reproductive
stage and postmenopausal stage. Three subgroups, containing approximately 30 patients each,
received one of three vagitorie formulations for 5 days during which the effects on
subjective and objective symptoms were monitored.
Phase:
Phase 4
Details
Lead Sponsor:
University of Sarajevo
Collaborators:
Institution for Health Protection of Women and Motherhood University of Tuzla