Use of a Novel Fibrin Sealant in Total Knee Arthroplasty

• Status: Completed
• Trial end date: 2015-08-01
• Target enrollment: 0
• Participant gender: All

Summary

Applying a fibrin spray, after knee device implantation, will help in reducing patient blood loss and decrease the drop in both hemoglobin and hematocrit levels. Also, with decreased blood loss there should be a reduced need for blood transfusions.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Rush University Medical Center
• Treatments: Fibrin Tissue Adhesive

Criteria

Inclusion Criteria:

• Patients must be male or female of any race

• Ages 18-80 years old

• Patients must be undergoing an elective, primary knee arthroplasty performed by the principal investigator

Exclusion Criteria:

• Allergy or intolerance to the study materials

• Surgical intervention during the past month for the treatment of the painful joint or its underlying etiology

• History of previous surgeries on the affected joint including previous arthroscopy (open surgeries)

• Women that are pregnant or may become pregnant

• Patient declines to participate