Using Intranasal Midazolam (INM) and Lidocaine for Uncooperative Children

• Status: Completed
• Trial end date: 2018-10-10
• Target enrollment: 0
• Participant gender: All

Summary

Aims: The objective of the current study was to evaluate the effectiveness of topical lidocaine in relieving pain related to INM administration.

Design: This was a blinded, randomized placebo-controlled trial. Sixty-three uncooperative children, aged 4 - 11.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Tishreen University
• Treatments: Lidocaine; Midazolam

Criteria

Inclusion Criteria:

• uncooperative children scored 1 or 2 on Frankle Scale.

• had no medical history of neurological or cognitive alterations.

• No facial deformities.

• ASA Classification I.

• requiring dental treatment under local anesthesia.

Exclusion Criteria:

• known allergy to midazolam or any other benzodiazepines.

• upper respiratory tract infection with nasal discharge.