Overview

Using PET Scans to Study Brain Receptor Occupancy of BIIB014 in Healthy Male Volunteers

Status:
Completed
Trial end date:
2008-04-01
Target enrollment:
Participant gender:
Summary
To establish the extent to which BIIB014, following 8 to 12 consecutive days of dosing at selected dose levels, occupies the brain's A2A receptors. Receptor occupancy will be assessed by PET scanning using a radiolabelled tracer.
Phase:
Phase 1
Details
Lead Sponsor:
Biogen
Treatments:
3-(4-amino-3-methylbenzyl)-7-(2-furyl)-3H-(1,2,3)triazolo(4,5-d)pyrimidine-5-amine
Adenosine
SCH 442416