Utility of Liposomal Bupivacaine Transversus Abdominal Plane Block for Open Myomectomy

• Status: Recruiting
• Trial end date: 2023-01-01
• Target enrollment: 0
• Participant gender: Female

Summary

The study team will be randomizing patients presenting for open myomectomy to either received transversus abdominal plane blocks with either liposomal bupivacaine or standard bupivacaine. The study team will be analyzing the impact of local anesthetic on opiate consumption as the investigator's primary endpoint with other secondary endpoints.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Icahn School of Medicine at Mount Sinai
• Treatments: Bupivacaine

Criteria

Inclusion Criteria:

• Not pregnant

• Weight over 50kg presenting for open myomectomy

• No history of allergy to any study medication

• No history of malignant ventricular dysrhythmia, epilepsy, seizure disorder, or chronic pain syndrome other than pain from myomas

• No history of drug or alcohol use or abuse disorder or pre-existing liver disease.