Vaginal Dinoprostone Versus Vaginal Misoprostol Prior to Diagnostic Office Hysteroscopy in Postmenopausal Patients

• Status: Completed
• Trial end date: 2020-02-10
• Target enrollment: 0
• Participant gender: Female

Summary

To compare the effectiveness of vaginal dinoprostone and vaginal misoprostol with placebo in minimizing the pain experienced by postmenopausal patients during diagnostic office hysteroscopy and to assess the ease of insertion of hysteroscope as reported by the hysteroscopist.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Cairo University
• Treatments: Dinoprostone; Misoprostol

Criteria

Inclusion Criteria:

• Menopausal patients with an indication for office hysteroscopy (postmenopausal bleeding or abnormal ultrasound findings)

Exclusion Criteria:

• Nulliparous patients

• patients with cervical pathology

• retroverted uterus (detected by transvaginal ultrasound)

• previous cervical surgery

• patients with severe vaginal bleeding

• allergy or contraindications to dinoprostone or misoprostol therapy (asthma, liver, kidney, or heart disease).